目的 分析老年慢性心力衰竭住院患者的临床特点及药物治疗情况,为老年慢性心力衰竭患者的临床药物治疗提供依据。 方法 回顾性分析2013年10月至2014年10月北京大学人民医院心内科普通病房的慢性心力衰竭患者共68例。根据年龄分为老年组和非老年组,收集患者的相关临床基线资料和出院时药物治疗情况。结果 与非老年组相比,老年组慢性心力衰竭患者病情相对较重、肝肾功能减退、血钠偏低、β受体阻滞剂达到目标剂量的人数相对较少、联合用药情况较多。 结论 临床上应加强对老年慢性心力衰竭患者的关注,结合老年慢性心衰患者的病情特点慎重选择药物治疗,同时注意药物的不良反应和相互作用,加强指导,以改善患者预后。
Abstract
OBJECTIVE To investigate the clinical characters and the situation of oral drug therapy in elderly chronic heart failure patients. METHODS The survey was conducted among 68 chronic heart failure patients who were hospitalized between October 2013 and October 2014 in Peking university people′s hospital. Data were collected and statistically analyzed concerning the clinical characters and the oral drug therapy between the elderly and non-elderly groups. RESULTS Worsening of heart function was more significantly in the elderly chronic heart failure group than the non-elderly group. There was a tendency of multiorgan statement represented by hepatic and renal function to decrease with age. Both the level of serum and the percentage of those proper for beta blocker arrived to the minimal target dose were lower in the elderly group than in the matched group. Combined treatment of different drug was more common in the elderly group. CONCLUSION The physiological functions of elderly patients decreased and the patients often had many concomitant disease. It is very important to pay more attention to drug selections, drug interactions and adverse reactions to optimize the treatment plan to improve the quality of life and the prognosis of these elderly chronic heart failure patients according their clinical characters.
关键词
老年 /
慢性心力衰竭 /
临床特点 /
药物治疗
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Key words
elderly /
chronic heart failure /
clinical character /
drug therapy
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中图分类号：
R541.6
R972
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